An alkaloid isolated from the corn lily (Veratrum californicum) is a Sonic Hedgehog gene pathway antagonist with potential anticancer properties
- Catalog No: APH-05014
- CAS Number: 36069-45-1
- Chemical Formula: C29H47NO3
- Molecular Weight: 457.70
- Purity: > 95% determined by HPLC
- Appearance: White to off-white crystals
- Solubility: Soluble in ethanol and methanol
- Stability: Stable over extended period at -20°C.
- Storage: -20°C
- Shipping: On ice (5°C)
- Handling: Avoid exposure to skin and eyes.
Source:
Muldamine is a phytosterol steroid isolated from the corn lily (Veratrum californicum) that grows wild in the mountains and deserts of Nevada and California. Muldamine is closely related to Cyclopamine.
Aphios isolates and manufactures muldamine utilizing near-critical and supercritical fluids using CXF and CXP enabling technology platforms followed by proprietary segmentation chromatography.
Biological Activity:
Certain biological properties of Muldamine are similar to those of Cyclopamine.
References:
Gaffield W, Wong R, Lundin R and Keeler R. (1982). Structure of the steroidal alkaloid muldamine and its deacetyl derivative. Phytochemistry. 21 (9): 2397–2400.
Keeler R. (1971). Teratogenic compounds of Veratrum californicum (Durand). 13. Structure of muldamine. Steroids. 18 (6): 741–752.