Dr. Trevor P. Castor, PhD
Founder, President and Chief Executive Officer
Dr. Trevor P. Castor is President and CEO of Aphios Corporation and subsidiaries including Aphios Pharma LLC, North Reading, MA. He has over 35 years of diversified experience in technology and business development, management, marketing and finance in the pharmaceutical and biotechnology industries. He graduated from the University of California, Berkeley with a Ph.D. in Mechanical Engineering and a MSc in Chemical Engineering, and a BSc in Chemical Engineering summa cum laude from the University of Toronto, Canada. He studied Business Administration at St. Mary’s College, Brooklyn, NY, and Harvard University Extension Program, Cambridge, MA. He is the author of 86 issued and 43 pending patents on nanotechnology drug delivery and other enabling technology platforms, and enhanced therapeutic products as well as several peer-reviewed publications. His research has been funded by competitive NIH, NSF and NIST grants, and he has been an ad hoc NIH reviewer for more than two decades. He has collaborated with several multinational pharmaceutical companies including Eli Lilly, BMS, Novartis, Pfizer and Merck-Millipore-Sigma, and financial institutions such as the Bank of New England, the New England Life Insurance Company and the United Nations.
Dr. Christopher D. Breder, MD, PhD
Fractional Chief Medical Officer | Member, Board of Directors | Scientific Advisory Board
Dr. Christopher D. Breder is a highly accomplished physician-scientist with over 20 years of leadership experience spanning the U.S. Food and Drug Administration and the global biopharmaceutical industry. He brings deep expertise in clinical development, regulatory strategy, and safety assessment across a broad range of therapeutic areas, including neurology, anesthesiology, and rare diseases. At the FDA, Dr. Breder served as Medical Officer and Lead Medical Officer, where he oversaw more than 500 Investigational New Drug (IND) applications and contributed to multiple New Drug Application (NDA) and Biologics License Application (BLA) approvals. His work included key roles in regulatory decision-making, safety evaluation, and cross-disciplinary leadership on complex drug development programs. In industry, Dr. Breder held senior clinical development leadership roles at Bristol Myers Squibb, Supernus Pharmaceuticals, and Sunovion Pharmaceuticals. He has successfully built and led clinical development organizations, designed and executed global clinical programs, and advanced multiple therapeutic candidates from early-stage development through regulatory approval and lifecycle management. Dr. Breder has advised biotechnology companies, investors, and legal teams on clinical strategy, regulatory pathways, due diligence, and risk assessment. His unique dual perspective—combining regulatory insight with industry execution—positions him as a trusted advisor in advancing innovative therapeutics efficiently and strategically. At Aphios, Dr. Breder provides executive leadership in clinical development and regulatory strategy, supporting the advancement of the Company’s pipeline and enhancing its ability to achieve key value inflection points.
Dr. Judith L. Palmer, PhD
Director of Regulatory and Clinical Affairs
Dr. Judith Palmer-Castor is a behavioral health scientist with over 20 years of research, clinical and regulatory experience in industry and academia. Dr. Palmer-Castor was a Project Director on a NIH-funded Adolescent HIV/AIDS Clinical Trial Network Project at Children’s Hospital, Harvard Medical School, Boston, MA. She was also a consulting scientist for Mass General Hospital, Harvard Medical School—Division of Global Health and Human Rights, Boston, MA, and has held similar behavioral health, research, and clinical positions at Northeastern University, Boston, MA, SAMSHA, CDC, Atlanta, GA, as well as other non-profit health and human service agencies. Dr. Palmer-Castor graduated with a Ph.D. in Policy with an emphasis on Behavioral Health and Adolescent Development from Brandeis University, Waltham, MA, and M.S. and B.S. degrees in Psychology from Santa Clara University, CA.
Catherine A. Prillo
Chief Financial Officer
Catherine A. Prillo has over 30 years of experience in financial accounting, controls, and management. She was most recently CFO and VP of Accounting at an internationally-renowned retail organization where she led the financial group including Corporate Controller, Treasury, Insurance, Budgeting, Compliance and Controls, and successfully completed IPOs, a management-led leveraged buy-out, recapitalization to a Private Equity group and the sale of the Company to a strategic buyer. She graduated cum laude with a Bachelor of Commerce with a major in Accounting & Business Management from Concordia University, Quebec, Canada.